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Common Drug Q&A » Arthritis » Celecoxib

Celecoxib

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Q: Has anyone taken Celecoxib and what was the outcome?
I’ve been prescribed this by my specialist. Is it as bad as the side affects mentioned on other websites? Ectoricoxib gave me heart palpitations so they were no good!

A: There has been a lot of controversy surrounding anti-arthritics of this type, the coxibs and several have been withdrawn due to concerns about cardiac ( heart ) toxicity. Some of them were very effective and many patients did get a lot of benefit. When I was using them, when they were still fashionable, and before most of the concerns surfaced, I tended to avoid celecoxib as I found it to be the least potent drug in the group.

Q: can you take celecoxib as and when you need it , or do you have to take it constantly?
have been taking celecoxib and find it tiring taken with gabapentin . rather than take celecoxib all the time ,i would like when i really need it.just want to know will it be effective ?
would ask my doc, but i’d like an andwer soon not in a weeks time..
thanks for any help ..

A: The ‘coxibs’ ( COX-2 drugs) are an interesting group of anti-inflammatories, they were originally marketed as safe and with a much reduced risk of GI bleeding, they were designed for long term use. After many years of use it became clear that they all had a tendency to increase cardiac risks. 2 or 3 were withdrawn, but celebrex remains available.

It is now used rarely and generally more by specialists than GPs. The first entry on its data sheet warns the clinician to consider the risks of its use. Under administration the first instruction is “As the cardiovascular risks of celecoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used.”

This of course answers your question and hopefully will also ensure that you pop to your GP and discuss its use in general!

Q: what would happen if i take Tramadol 100mg tabs with Celecoxib 200mg ( brand name is COBIX-200)?
I’m 45 yers old and currently on Tramadol for about 1 year
I’m Insulin dependent
My physician doesn’t know that I’m on Tramadol,
I don’t drink, but what would happen if i drink alcohol

thank you

A: There a few issues involved in your situation that relate to drinking alcohol.

First, alcohol can raise your blood sugar, which may be problematic since you are diabetic. As long as you limit your intake to 1 or 2 servings, this probably won’t be a serious problem.

Secondly, celecoxib is an NSAID (the same class of drugs as aspirin, ibuprofen, etc.) On their own NSAIDs can cause irritation to the lining the of the stomach – for example, elderly people experiencing stomach bleeds while on chronic aspirin therapy. Alcohol is also irritating to the lining of the stomach. When you combine the two, you increase your risk for developing complications.

Thirdly, tramadol is a medication that causes CNS depression, with symptoms such as drowsiness, confusion, and impaired coordination. Alcohol is also a CNS depressant, so in this case as well it can increase the risk of complications with the tramadol.

While none of these are reasons to completely avoid alcohol, they put you in the situation of needing to be especially cautious if you do choose to drink.

It’s always a good idea for you physician and your pharmacist to know all the medications you are taking. This helps to prevent dangerous drug interactions and complications.

Q: What is the classification of Celecoxib ?

A: It is a COX-2 inhibitor. It is part of the general category of
non-steroidal anti-inflammatory drugs (NSAIDS). It is used mainly for treatment of rheumatoid arthritis joint pain

Q: Celecoxib drug is not using in india but other countries r using more y
full detail about celecoxib

A: actually there may be two reasons.
1. the company manufactured should have patent right for that. or
2. the standards for this drug is not according to indian standards

Q: what is the use of celecoxib celcox?
please help me… i want to know more about this medicine.. is it safe for us human? what are the disadvantages and advantages of this med? what is this medicine for? It is used for what? thanks..

A: It is an NSAID or non-steroidal antiinflammatory drug. Shares the same mode of action as Aspirin, without the risk of ulcers and stomach irritation. Commonly prescribed for arthritis pain.

Q: my wife is taking these pills which one is causing nightmares: oxycodone,percocet, celecoxib, diazepam(valium)?
my wife just had surgery an is now taking these pills. she has nightmares now an we are trying to pinpoint the source to either lower the does or find out if there is an alternative.

A: Despite how many others are answering saying it is the Valium, I would disagree. Valium suppresses REM sleep which means you do not have dreams. This is why Valium is sometimes used to induce amnesia before surgery.

I was on Effexor and Xanax and the Effexor was giving me dreams (although not nightmares) every night. Since my doctor has switched me from Xanax to Valium, I no longer have dreams despite still being on Effexor.

You really need to speak to a doctor as it’s hard to pinpoint where problems are initiating when taking so many drugs. Dosages, when the drugs are taken in relation to each other, meal times in relation to dosing, etc., can all affect medication side effects.

You should also inquire as to the purpose for each medication. Perhaps the Valium is being prescribed to suppress nightmares but it is not working, in which case some tweaking needs to be done.

Q: The Drug interaction site says there is a interaction between the drug vicodin and celebrex?
Can anyone put the following in layman’s language?
Coadministration with celecoxib may increase the plasma concentrations of drugs that are substrates of the CYP450 2D6 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by celecoxib

A: Just call the nearest 24 hour pharmacy to you and ask them to explain the interactions to you. With the competition to get customers these days, they will help you.

Q: I have a bad back, I’m currently taking 750mg of vicodin. But have been thinking abouting switching.?
I have a bad back, I currently have been taking 750mg of vicodin. But have been thinking abouting switching to another Med, like 200mg Celecoxib, or 50mg of Tramadol HCI (That’s all the on-line store stocks) . What one would be better? And is the strenth the same as the Vic 750mg?
The other Meds would be less expensive than what I’m paying now.

A: Vicodin 7.5/750 and celecoxib are completely different types of meds. Vicodin is a combination of hydrocodone (an opioid analgesic) and acetominophen (a mild analgesic/antipyretic) this is indicated for moderate nocioceptive pain. Celecoxib is a COX-2 inhibitor class antiinflammatory. They do not treat the same issue and therefore cannot be compared properly for head-to-head pain relief. If celecoxib relieves the pain it is by decreasing the inflammation primarily. Hydrocodone relieves pain by decreasing the perception of pain in the brain.

Generally hydrocodone would be expected to relieve the pain from injury more than celecoxib. However if the pain you feel is due to inflammatory changes (and most pain conditions have some component of inflammation) the celecoxib should be more effective. But if I was to select medications for chronic back pain, I would most likely put the patient on both celecoxib and an opioid analgesic.

Ultram is a opioid derivative and has similar mechanism of action to hydrocodone. Some studies have found the tramadol to be more effective than hydrocodone in managing moderate pain.

My experience with these drugs would indicate that while all patients have a reasonably similar response to hydrocodone and celecoxib, tramadol response is very patient dependent. While one person taking tramadol would get great response another would seem to have almost no relief. However, when tramadol works it is very effective.

NOTE: Tramadol may lower the seizure threshold in some patients and there has, therefore, been shown an increased seizure risk while taking this medication. tramadol should not be taken by persons with a history of addiction to drugs or alcohol.

Please see the precautions before taking any medications. All these medications are dispensed in the US by prescrition only. Do not allow yourself to be given these medications by an online, unseen provider with no knowledge of your condition. Seek your doctor’s advice before switching to a new med or starting any medication.

Q: pain or weak in my knee?
i feel infirmity(weak) in my knee.doctor say your cartilage rubed.at first my doctor gave me celecoxib.
and yet he gave me a medicine.i can’t read his handwriting.but ist like “pias clu”.what is that medicine?(excuse me,i can’t write english good)

A: call a pharmacist and ask them?

Q: how reduce pain?
I am 18 & my menstrual period is too painful that I can’t do anything.I have tried Celecoxib tc 100,Ibuprofen 400, Acetaminophen, Panadol& Diclosinfort but they didn’t work unless I took 1 per 4 hour t then stomachache started. According to my doctor the Sonography was ok & with no problem.What should I do?

A: Hi,

Dysmenorrhoea is the clinical term for painful menstrual periods when cramps are frequent and severe. Primary dysmenorrhoea results from uterine contractions that occur normally during periods,

The initial treatment is focused on the relief of pain. Anti-inflammatory drugs may be helpful; this includes aspirin, nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen and indomethacin.

In some severe cases, and with disorders such as endometriosis, oral contraceptives may be helpful. They are used in this case to regulate the hormone levels in the body. They may be prescribed even for girls who are not sexually active.

Women who continue to have severe dysmenorrhoea despite the use of NSAIDS and/or oral contraceptives may require laparoscopy for further evaluation.

Mild analgesics are usually effective in treating dysmenorrhoea and oral contraceptives generally control severe cases. Dysmenorrhoea associated with a disease state responds to treatment of the primary problem. A doctor should be contacted if the menstrual cramps are severe or if the discomfort lasts for more than 2 or 3 days.
In addition to medical therapy, there are a number of other ways that can help ease the pain of menstrual periods like:

Regular exercise

Direct heat application in the form of a heating pad, hot water bottle or warm bath may be soothing.

Massage of the lower abdomen and/or lower back

Relaxation exercises

Adequate sleep

Drinking plenty of water

Avoiding caffeine as in coffee, tea, sodas and chocolate just before and during the period

Eating plenty of green leafy vegetables and whole grains

Enjoy Life

Q: fatal drug combinations?
just need to know which of these drugs from this list has a fatal combination:

Fluoxetine
Warfarin
Celecoxib
Captopril
Moduretic

thank youuu

A: Pardon my ignorance, but WHY would you even be asking this question? I suggest you call your local mental health clinic and make an appointment with a counselor or therapist. You very obviously need it.

Q: Need help with this problem!!?
A patient is taking 1,500 ug (?) of Celecoxib (an anti-inflammatory medication) per day. Convert this dosage into milligrams and grams. Show in scientific notation.

Please explain how you got the answer. Thanks!~
Would it be 1.5 mg and 1.5×10^-3 g?

A: ug = microgram

microgram = 10^-6 g

Milligram = 10^-3 g

and g = g

so 1500 Micrograms going to milligrams: you would just move 3 decimal places to the left since you are going from smaller to bigger so

1500 micrograms(ug) = 1.5 milligrams

to go from 1500 micrograms to grams: you would moce 6 decimal places over to the left since you are going from smaller to bigger units.

1500 micrograms(ug) = .0015 grams

Hope that helped.

Q: reduce pain?
I am 18 & my menstrual period is too painful that I can’t do anything.I have tried Celecoxib tc 100,Ibuprofen 400, Acetaminophen, Panadol& Diclosinfort but they didn’t work unless I took 1 per 4 hour t then stomachache started. According to my doctor the Sonography was ok & with no problem.What should I do?

A: Specific treatment for dysmenorrhea will be determined by your physician based on:

* your age, overall health, and medical history
* extent of the condition
* cause of the condition (primary or secondary)
* your tolerance for specific medications, procedures, or therapies
* expectations for the course of the condition
* your opinion or preference

Counseling with your physician regarding symptoms may increase understanding and lead to activities for stress management. Other possible treatment protocols for managing dysmenorrhea symptoms in young women may include the following:

* prostaglandin inhibitors (i.e., nonsteroidal anti-inflammatory medications, or NSAIDs, such as aspirin, ibuprofen) – to reduce pain

* acetaminophen

* oral contraceptives (ovulation inhibitors)

* progesterone (hormone treatment)

* dietary modifications (to increase protein and decrease sugar and caffeine intake)

* vitamin supplements

* regular exercise

* heating pad across the abdomen

* hot bath or shower

* abdominal massage

Q: Hurt Collar bone bad in China today. Doctors no help. Need yahoos advice. so painful?
I have been riding my new moutain biking for 2 weeks now. Like 80 km a day weekdays after not riding for 8 years and being out of shape. Someone burglularised my home and stole 8 years of my life work 3 weeks ago I decided I was going to bury myself in my mountainbiking, get my healthback and now today the worst thing happened.

First woke up and am scared my youngest child might have the pigflu as he is showing flu symptoms…

Then I left and rode 35 kilometers on one of my fastest commutes and had an accident. I was in a small back alley street and I saw this guy on the side of the road trying to walk out in front of me it looked like on the shoulder of the road..

Then blam I hit a speed bump the same color as the street.. totally missed it and indo’d over my front handle pars feet locked in place and slammed head and shoulder into the pavement.

The Chinese walked around me as if nothing happened. I walked for about a kilometer then felt the most horrific pain I have ever felt.

Went to the hospital.. and then the doctors tok an exray and said somethinglike two tendons n my collar bone were ripped and I would need a surgery. First they said 10-15000 rmb, then their boss came in and saw I was a foriegner and was like “oh no… thats like 25000 rmb”

This is some serious cash. I can tell you that this hurts soo bad. They gave me morphine and some other pills Celecoxib.

That didnt really do anthing that I can tell. I cant stand up and have to hold my arm up and out words of my body in order to not feel any pain… I mean not bad pain. Even when I walk. MY woman has to hel me piss as I cant doi it myself. They put some kind of harness on me and a free hanging splint. I am under the impression they dont know how to make splints because I cant do anything unless Ihold my arm up with my other arm.

I need You help.

Can you help me with the following questions?

1)I can attach a picture of the x-ray and can someone tell me the name of what I have in English?

2) Whats a good a good painkiller,

3) how to make the proper splint?

4)and is an operation necessary?

And what is it that I have in English?

The google translation says:

“The right shoulder is sorrowful place right shoulder lock joint space widened, distal clavicle upward shift”

I hurt so bad. i need to take care of my two children and 25000 is so much/

5) Will I ever be able to ride again?

6) It hurts so bad.. when will it stop hurting?

Thanks for your help

Robert …

Dead sad. Hurting.
you can see xrays here
http://forums.mtbr.com/showthread.php?p=6352468#post6352468
THanks for your advice so far. Another Chinese doctor said it needs to be operated.. but they are so financially motivated. The last thing in the world i want to do if I dont have to is put metal pieces in my body. Question… I understand the ligaments are torn on the collar bone.. can you tell me if my shoulder is out of its socket/dislocated? if so does someone have to put it back into the socket? or can I just leave it alone and everything will heal on its own?

http://thecenterofthenet.com/IMG_0001.jpg
http://thecenterofthenet.com/IMG_0002.jpg

http://thecenterofthenet.com/smaller.jpg

A: You have an AC Separation. It’s no big deal. In the United States we just treat it with a simple arm sling until the pain goes away, also put some ice on it. You basically tore the acromial clavicular ligament and now the clavicle or collar bone sticks up. There are orthopaedic doctors who might want to operate on them if they need to buy new shoes for their kids but it’s not a big deal. It hurts like a mother but it will go away. My suggestion to you is next time fall on the other one and then your shoulders will look normal. ; )

I remember a Boston Bruin coming into the Emergency Ward having this when he hit the boards and the orthopaedic residents wanted to operate on it and then the team sports medicine guru and orthopaedic shoulder professor ermeritus, Harvard Medical School Carter Rowe, MD Lol, he said for what reason so he can do it again! He said it wouldn’t make any sense until after he gives up hockey.

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