Common Drug Q&A » Blood Thinner » Plavix Drug

Plavix Drug

A: Yes. Start here:

http://www.pparx.org/

Q: What exactly does the drug Plavix do?
My husband is having heart issues and I’m hoping the Dr doesn’t prescribe Plavix for him, I looked up my insurance and it’s 1800.00 for a 3 month supply and no other generic is listed for this medicine.
He has an irregular heartbeat.

A: Clopidogrel bisulfate (Plavix) prevents thrombocyte (platelet) aggregation and agglutination meaning that it prevents so-called ‘white’ blood clots in arteries. [Blood clots in veins are composed primarily of erythrocytes - red blood cells - and are therefore referred to as 'red' blood clots.] Clopidogrel is not typically prescribed for an irregular heart rhythm so there must be more to the story than you are aware of. Aspirin has effects similar to clopidogrel and aspirin and clopidogrel in combination are utilized after placement of stents in coronary arteries. I would wonder if aspirin would be as effective as clopidogrel but as stated above there really is no clear indication for either in your question. I would suggest that you ask your husband’s physician for further education about the indication for the drug as well as its advantages and disadvantages. I would also ask if something less expensive such as aspirin would work as well. If I may be of further assistance please let me know. I wish you and your husband the very best of health and in all things may God bless.

Q: Can the drug Plavix cause muscle problems such as spasms or sharp pain in back or shoulder?

A: its due to gastric related problems of plavix

Q: Is there a generic drug for PLAVIX? Is there anything comparible?
The cost for PLAVIX is very high. It’s hard for me to pay the high prices, and I need the drug.

A: At this time there is no generic for Plavix. There are other drugs in same class but they tend have a different mechanism of action. You should ask your prescribing physician why exactly Plavix is working for you. Depending on the reason you may be able to find something better for your situation.

Q: Any cheap alternatives to expensive anti-clotting drug Plavix?

A: Here’s the DL:

Plavix is NOT an anti-clotting drug (in medicine, the semantics of this matter). Plavix is an anti-platelet agent. Coumadin (warfarin) is an anti-clotting agent. They work completely different and have different purposes. Some patients will be on both, others will only be on either or.

Plavix has a cousin, Ticlid (ticlodipine). Ticlodipine is available generically but has some severe disadvantages and as such, is rarely ever used now that Plavix is sold. Ticlodipine came out first and think of it as the first child that the parents made all the big mistakes with. Ticlodipine is known to cause a dramatic drop in several of your white blood cells (very key parts of your immune system that fight infections- it can even wipe out nearly all of your immune system). Ticlodipine is also known to cause some pretty severe bleeds.

In fact, ticlodipine has a Black Box Warning on it because of the impact on WBCs and the increased risk for bleeds. A black box warning is the strongest warning/precaution that the FDA can issue without pulling a drug off the market or making it available directly from the manufacturer only. Plavix does not have these black box warnings or severe side effects that ticlidopine does, so it is regarded to be much safer. Plavix also has a lot of good data and evidence for use in certain stroke patients, heart attack survivors, and those that receive stents (among other uses). Honestly, I can’t remember selling ticlodipine at all in the last 3 years. And I highly doubt that your doctor would agree to switching you from Plavix to Ticlid.

Some of you reading this will remember that Plavix’s generic, clopidogrel, became available for about four days and then it was pulled from the market. Plavix is actually still under patent. A generic company found some loophole in the wording and manufactured and sold generic clopidogrel. Since Plavix is still under patent, the Plavix manufacturer sued the generic company and production came to a stand still. The drug industry provides such large profits that the generic company still made a boat load of money with only four days of clopidogrel on the market and a lawsuit to pay out. Crazy, huh?

A new cousin to Plavix and Ticlid is set to come out very soon. It’s name is Effient. I know it was undergoing priority review by the FDA a couple of months ago and I’m not sure where it is at right now. This may signal that Plavix will be coming off patent soon.

I don’t know how long Bristol-Meyer’s patent for Plavix will last but hopefully it will be up soon. It’s a great drug that saves lives but I know its crazy expensive and I’m aware that some patients just can’t afford it.

Q: anyone know if the drug plavix is available and the cost in philippines?
thanks for the answer.. I am assuming it is php $

A: rose pharmacy it is P 116.50 per piece.

mercury drug it is P 123.50 per piece.

ooops…. it is philippine peso.

Q: If you have a stent that is drug coated will you take plavix and aspirin forever?
Is it safe to stop plavix if you had a stent put in 2 years ago? My husband’s Dr. wants to take hime off plavix and just have him take an aspirin daily. I disagree and think he should err on the side of caution and take both. Does anyone know for sure?

A: Generally, you should follow your doctor’s advice. However, it’s a good idea to get a second opinion if you’re not sure about a decision.

You might want to check out this site to give yourself some more information to inform your discussion with the doctors:

http://www.smart-heart-living.com/cardiac-stent.html

Hope this helps… good luck!

Q: How long should someone with a drug-coated stent take Plavix?
I have J&J’s Cordis Cypher stent. I am 64 years old, received the stent 23 months ago, and have only one stent.
I also take one 81 mg. aspirin daily.

A: Many cardiologists recommend lifetime Plavix, as long as there are no adverse effects (financial or physical).

Q: what are the ingredients in plavix the drug that have bad effects when you also take coumidin?

A: http://www.drugs.com/cons/plavix.html

Q: Is clavix and plavix basically the same drug?and same action?
Im asking abt this coz my dad is already on plavix and cant afford it now..so is it ok to get clavix frm abroad?

A: Yes, both are the same anti-platelet drug, clopidogrel hydrogen sulphate.

Q: Generic drug for Plavix?
Is there any truth to the fact the generic drug for Plavix has now been taken off the market? The pharmacist said the generic drug was released for sale too fast and has now been pulled so we have to buy the more expensive Plavix again. Doesn’t sound right to me but someone may know the truth. Can we here from them now?

A: Legal issues caused the company making generic Plavix to stop marketing it. The contention was copyright infringement.

It’s still up in the air as to when it will be available again.

Q: Drug eluting stenting and G6pd-Patients, What about asprin and Plavix treatment, ist possibel or not?

A: what is your question?

Q: Is coumadin really that bad of a drug?
Is coumadin really as bad as the reputation it has and is another drug like plavix as effective or any safer?

A: Plavix is not a substitute for Coumadin when Coumadin is what you need. If you have a hypercoagulable condition, the chances of coumadin helping you are FAR greater than the chances of it hurting you. The important thing is to take the medication as prescribed, stick to a regular diet, and follow your doctor’s instructions for routine blood monitoring. Below are a couple of links that discuss the importance of watching your diet, and which foods are high/med/low in Vitamin K (which is the antidote to Coumadin.)

Hope this information helps you out a little bit.

http://www.mayoclinic.com/health/warfarin/AN00455

http://www.drgourmet.com/md/relativewarfarinlist.pdf

Q: I have recently started taking PLAVIX. Is it a good, safe drug?

A: Yes PLavix is a good drug. I have found that many patients do “well” with this drug. Here is a small article from John Hopkins University that gives you a little insite to the drug. Please follow your doctors orders and always take what you read on the internet with a grain of salt. Here it is:

Newspapers have devoted less space to recent findings about treatments with aspirin plus Plavix than they have to current sporting events. Yet this combination of two anti-clotting drugs has generated clinical results every bit as exciting as a 90-yard punt return.
Because both aspirin and Plavix prevent blood platelets from clumping up and blocking a major artery supplying blood to the heart or brain, they can be used to lower heart attack risk. But now, findings of the CHARISMA trial indicate that when aspirin and Plavix are combined they can be even more beneficial to some.

The CHARISMA trial compared cardiovascular outcomes in two groups of patients: one group had multiple risk factors but no known vascular disease; the other group had known vascular disease involving the coronary, cerebral, or peripheral arteries. Subjects from both groups were treated over a 30-month period either with aspirin alone or with aspirin plus Plavix.

Among the high-risk/no-disease participants taking the aspirin-Plavix combination, there was a trend toward worse cardiovascular outcomes, as well as a significant increase in episodes of moderate bleeding.

By contrast-and here’s the payoff-the risk for cardiovascular events was significantly lower among those with known vascular disease who were taking both drugs in combination.

Although it may be dangerous to reach general conclusions from the results of a single study, the findings suggest that the antiplatelet combination is useful for, and should be continued in, people with known vascular disease. On the other hand, aspirin alone, rather than the combination of aspirin plus Plavix, appears a better choice for people who have risk factors but no known vascular disease.

Q: what drug was used before plavix?

A: Before Plavix,which affects the platelets and has an anti-clotting effect which helps prevent M.I’s and strokes,Coumadin/warfarin was the only agent available. It is a so-called blood thinner and was derived from rat poison which would cause rats to hemorrhage internally and die.Coumadin is still used widely because it is inexpensive and some patients cannot tolerate Plavix.Aspirin is also sometimes used to prevent heart attacks,but used on a regular basis has a tendency to destroy the stomach lining and cause internal hemorrhage.

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