Common Drug Q&A » Pain » Orphenadrine


I live alone so I am always nervous when I get into more serious medications like this. What should I expect?

A: Very few side effects if any. Surely not loopy and not like soma where it relaxes whole system and makes you feel sick.

Q: Orphenadrine, have you ever had any bad side effects from it?
What were they and how long were you taking these?

(same thing as Norflex)

A: SIDE EFFECTS: Stomach upset, headache, blurred vision, drowsiness, dizziness, lightheadedness, dry mouth, constipation, difficulty urinating or flushing may occur. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor immediately if you develop: a rapid heart rate, fainting, fever, breathing difficulties, skin rash, mental confusion, depression. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. Also limit your intake of alcoholic beverages which will aggravate these effects. Use caution performing tasks requiring alertness if this medication causes you to feel drowsy. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor if you have: kidney disease, liver disease, bladder problems, heart disease, prostate trouble, ulcers, glaucoma, myasthenia gravis, allergies. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding. Limit the use of alcohol while taking this medication since excessive drowsiness or depression can occur.

Q: What would happen if someone take an orphenadrine but broke the pill up like it says not to?
extended 12 hour release formula 100 mg

A: You’ll bust at the seams and blow up.

Q: what is norflex orphenadrine citrate?
what happens if you take more than the recommended dosage? one of my friends decided to take it to get some sort of high and im just wondering if anything will happen.

A: Well Norflex is a muscle relaxant that also works as a pain killer. It is an opioid that will give the side effects of over dosing or mis dosing a strong pain killer. Like any medication, I would make your friend stop abusing them to get a high becuase there is always a chance of addiction.

Q: Is it ok to take darvocet and orphenadrine ( muscle Relaxer) at the same time?

A: Yes it is. There are no contraindications between the two pills so your safe. You’ll prolly feel extra drowsy and sleep, but there is no reason why you cant take the two together.

If you feel uneasy about taking the two at the same time, take one then an hour take the other. Darvocet is used to treat mild to moderate pain and although they say its ‘potent’ (only due to the fact it has a narcotic in it) its really a MILD to take.

Hope you feel better soon.

Good Luck.

Q: Can you take Orphenadrine, with an enlarged prostate?

A: Please don’t. It can cause urinary retention. You may have to go to the ER for catheterization if your develop retention.

Q: what does diphenhydramine/orphenadrine mean when it’s found in a toxicology report?

A: Diphenhydramine is an antihistamine/anticholinergic well known as the brand name Benadryl. It’s also used as a sleep aid in such preparations as Tylenol PM. Orphenadrine is very closely related chemically, but is used primarily as a muscle relaxant, under such brand names as Norflex.

Q: What is Orphenadrine used for?
I work at the same company aas my parents, who are divorced, and I was sitting in my dad’s office today and saw a bottle of pills sitting on his desk right next to the keyboard of the computer he was letting me use.

It’s called Orphenadrine and I was wondering what it is used for?

A: Orphenadrine is a drug used to treat pain, muscle spasm and other symptoms of injury and other problems. It is also used for treating some aspects of Parkinson’s Disease.
Orphenadrine is used to treat muscle injuries, skeletal muscle tension and rigidity secondary to afflictions such prolapsed discs and degenerative soft tissue disease especially in the lower back, neck, and joints. and other causes of muscle spasms, to potentiate the action of opioid analgesics against moderate to severe neuropathic pain, and it is also used to treat Parkinson’s disease.

Orphenadrine is also a component of various preparations for use against headaches of various types especially tension and histamine headaches. It is also helpful in many cases of fibromyalgia.

Let me know if u want to know more about it…..I guess that should help you

Q: my dad passed away and his toxicology came back with diphenhydramine/orphenadrine in his urine. what is that?

A: I’m so sorry to hear about your father, I will pray for you and your family. To answer your query, I’ll refer to the National Institutes of Health’s website…

Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication.

Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

Orphenadrine is used with rest, physical therapy, and other measures to relieve pain and discomfort caused by strains, sprains, and other muscle injuries.

Q: Orphenadrine and Wellbutrin?
If you take 400mg a day of Wellbutrin, and you took 100mg of Orphenadrine, would there be any negative reaction?

A: you can check drug interactions online, for eg

Q: taking orphenadrine 100mg for muscle spasm (worse one my doctor had ever seen) but gettin no long?
last week i woke up with my head hanging off the bed, needless to say i got a huge muscle spasm (went to the hospital b/c the pain was shooting into my shoulderblade & down my left arm to my elbow, in the awfulest pain ive ever felt, i cry so much) the doctor told me that the muscle spasm (they took “pictures”) and it was one of the biggest muscle spasms she had ever seen. they prescribed orphenadrine 100mg (take 1 daily every 12 hours for muscle spasms) but, i’ve already taken 2 pills, 3 of the IBU (600mg) and nothing has helped! sitting, or walking makes it hurt that much more, i only get relief when i lay flat, but when i wake up of a morning im stiff and in awful pain, its like nothing is long does it usually take for muscle relaxers to start taking full effect?

A: they should start helping soon,, it sounds like almost a disc is on a nerve, did they do an exray of the upper back area around the neck, if the pain does not go away remind your doc of that,,I have neck pain alot due to a car wreck, I know how you feel

Q: What is a good prescription muscle relaxer?
I am taking Norflex (orphenadrine citrate) 100mg twice a day right now and it is helping a little but I am wondering what would be bit stronger and wouldn’t knock me on my @ss. It should be specifically for targeting my neck muscles.

A: Cyclobenzaprine (Flexeril) works well.

Q: can i over dose on orphenadrine citrate ?
if so what will happen

A: yes, 2-3g will kill you. you will probably go into tachycardia, a seizure, or respiratory arrest…

don’t do it.

Q: orphenadrine citrate 100mg (norflex) versus orphenadrine comp tablet san (norgesic)?
What is the difference or is there really any? i was taking the 100mg tabs twice daily now im getting ready to go see a neurologist and the dr changed me to the orphenadrine comp tablet san – and i take them 3 to 4 times a day – starting today – should i expect any difference in how i will react to the meds>

I was trying to compare them on web sites and i pulled up one page that said manufacturer has stopped making them? are they less safe than the orphen citrate -

A: The difference is the ingredients: Norflex is indicated for muscloskeletal pain and only contains orphenadrine. Norgesic has that plus aspirin and caffeine. Unless you can’t tolerate either of the extra ingredients, you should be fine. Apparently norgesic is discontinued but I’m not sure why. However, if the neurologist made the change and is aware if the situation, it should be OK.

Q: is Orphenadrine a drug that can be abused i found 4 in my moms jewlry box and looked it up on the computer.?
it wasnt in a bottle and im wondering if she could be abusing them
could it cause weight lose
and lower appitite

A: Orphenadrine is used to treat pain and muscle spasms. If she normally doesn’t have chronic and intense pain/spasms, then there is the possibility that they could be being abused. I wouldn’t assume anything too fast though. Observe her behavior until you suspect there is a problem — and then bring it up to somebody.
Hope I helped,

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